Sepsis: definitions, epidemiology, and pathophysiology foundations

Apuntes

Seminar1www.thelancet.com Published online February 26, 2026 https://doi.org/10.1016/S0140-6736(25)02422-5 Published Online February 26, 2026 https://doi.org/10.1016/ S0140-6736(25)02422-5 Bloomsbury Intensive Care Medicine Institute, Centre for Respiratory Medicine, University College London, London, UK (Prof M Singer FRCP); Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA (Prof D C Angus FRCP); IHU PROMETHEUS, Comprehensive Sepsis Centre, General Intensive Care Unit, Raymond Poincaré Hospital, Garches, France (Prof D Annane MD); School of Medicine Simone Veil, University of Versailles Saint-Quentin-en-Yvelines, Paris, France (Prof D Annane); Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany (Prof M Bauer MD); Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA (Prof A C Kalil MD); Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Healthcare Institute, Boston, MA, USA (Prof M Klompas MD); Department of Medicine, Brigham a...