Biological membranes: structure, composition, and dynamics (Fluid Mosaic Model)

Apuntes

Class 2 Biological Membrane Fluid Mosaic model - Experimental Evidences that make up the model - Diffusion of membrane components - Types of transmembrane proteins - Integral proteins that mediate interaction - Membrane fusion Biological Processes - Characteristics of Biological Membranes (Goter y Grendel 1928) Extraction of erythrocyte membrane ghosts. 1- They are flexible Shape Changes 2- They seal themselves, Membrane fusion. Biological processes Exocytosis Phagocytosis Fecundation Route of infection Non-covalently assembled phospholipid monomers Anphipatic molecule Saturated Fatty Acid Unsaturated fats with double bonds In the hydrocarbon chain Structural model of fluid mosaic Nomenclature of the faces of the cell membrane Red: Cito-plasmatic Black: Exo-plasmatic Physical Properties of the Membrane (evidence) 1- The phospholipid membranes pure are similar to natural ones. 2- Mixture of phospholipids with a similar composition like natural membranes form bi-layer flat or liposomes provide spontaneous way (Fig 5-32). 3- Evidence of the structure of bilayer by X-ray diffraction, of the myelin membrane Experimental formation of pure phospholipid bilayers Black lipid membranes Solve...