Farmacoqu1mica

Apuntes

Farmacoquímica Universidad Autónoma de Yucatán 1 Farmacoquímica Facultad de Química UADY UNIVERSIDAD AUTÓNOMA DE YUCATÁN Key Concepts and Definitions Farmacoquímica Facultad de Química Químico Farmacéutico Biólogo Farmacoquímica Universidad Autónoma de Yucatán 2 Choosing a disease Choosing a drug target Identifying a bioassay Finding a lead compound Isolation and purification Structure determination Structure-Activity Relationships Identification of pharmacophore Improving receptors interactions Improving pharmacokinetics Toxicity testing Drug metabolism studies Patenting and regulatoriy affairs Clinical trials Chemical and process development Getting the drug to the market Farmacoquímica Universidad Autónoma de Yucatán 3 MEDICINAL CHEMISTRY Chemistry Area Organic Chemistry Life Sciences Medicinal chemistry concerns the discovery, the development, the identification and the interpretation of the mode of action of biologically active compounds at the molecular level. Emphasis is put on drugs, but the interest of the medicinal chemistry is also concerned with the study, identification, and synthesis of the metabolic products of drugs and related compounds IUPAC official def...