Biocompatibilidade Universidade do Minho 2024 - 25

Apuntes

Biocompatibilidade Universidade do Minho 2024 - 25 Codigo: BComp_2025 BIOCOMPATIBILITY Definition, Biomaterial - Tissue interaction Outline Biocompatibility – definition What is the so called Foreign Body Reaction ? What happens when biomaterials are implanted in the body? The cases of silicone and polypropylene Use of Drug Delivery Systems to control the Foreign Body Reaction Implanted biomedical devices reside within tens of millions of patients in the United States alone , and are involved in millions of new and revisionary surgeries every year . As such , they comprise a major component of modern medicine and are essential for many clinical applications ranging from hip / knee replacement , tissue repair / reconstruction , prosthesis and neural interfacing , controlled drug release , electronic pacing , vital sign monitoring , intraocular lens replacement , and cell encapsulation and transplantation . Unlike particulates , which may be phagocytosed and cleared by the innate ...