Tissue Rep

Apuntes

Tissue Repair PATH1016 PATH1016 Inflammation 2024-25 • Healing Process (Final phase of inflammatory response) • Tissue repair overlaps with inflammation and restores tissue structure and function after injury. • It can take two forms: 1. Tissue Regeneration, where injured parenchymal cells are replaced with the same cell type. 2. Tissue Replacement (Fibrous Tissue Repair), which involves connective tissue leading to scar formation or fibrosis in organs. PATH1016 Inflammation 2024-25 • Types of Structures in Body Organs and Tissues • Parenchymal tissues contain the functioning cells of an organ or body part (e.g., hepatocytes, renal tubular cells). • Stromal tissues consist of supporting connective tissues, blood vessels, extracellular matrix, and nerve fibers. • Extracellular Matrix includes the interstitial matrix, which is the space between cells in blood and tissue. PATH1016 Inflammation 2024-25 • Wound Healing by Primary or Secondary Intention • The process aims to fill the gap caused by tissue destruction and restore structural continuity. • Primary healing occurs in small, clean wounds. • Secondary healing involves larger tissue loss with contamin...