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Revista de Gastroenterología de México 91 (2026) 286---297 REVISTA DE ´ GASTROENTEROLOGIA ´ DE MEXICO www.elsevier.es/rgmx LETTER TO THE EDITOR Rebamipide as adjuvant therapy in Helicobacter pylori eradication regimens Rebamipida como tratamiento adyuvante en los esquemas de erradicación de Helicobacter pylori We have read with great interest the article, ‘‘The Fifth Mexican consensus on the diagnosis and treatment of Heli- cobacter pylori infection’’, by Remes-Troche et al., recently published in this journal.1 We congratulate the panel of experts for their comprehensive update and for the effort to emit recommendations in accordance with the national epidemiologic context. We would like to draw attention to an aspect that was not addressed in the document: the possible role of rebamipide as adjuvant therapy in Helicobacter pylori (H. pylori) eradi- cation regimens, particularly now that this drug is available in Mexico. Rebamipide is a gastric mucosal protective agent that increases endogenous prostaglandin and gastric mucus pro- duction, reduces oxidative stress and inflammatory cytokine production, and improves blood flow and mucosal repair.2,3 Experimental studies have also sh...
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